2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]-
ARQ-092
CAS: 1313881-70-7
Molecular Formula: C27H24N6
2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]- - Names and Identifiers
2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]- - Physico-chemical Properties
| Molecular Formula | C27H24N6 |
| Molar Mass | 432.52 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Boling Point | 700.8±70.0 °C(Predicted) |
| Solubility | DMSO: ≥ 40.2 mg/mL |
| pKa | 9.17±0.20(Predicted) |
| Storage Condition | -20℃ |
2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.312 ml | 11.56 ml | 23.12 ml |
| 5 mM | 0.462 ml | 2.312 ml | 4.624 ml |
| 10 mM | 0.231 ml | 1.156 ml | 2.312 ml |
| 5 mM | 0.046 ml | 0.231 ml | 0.462 ml |
Last Update：2024-01-02 23:10:35
2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]- - Reference Information
| biological activity | Miransertib(ARQ-092) is an effective, selective and orally bioavailable Akt allosteric inhibitor with IC50 values of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2 and Akt3 respectively. |
| target | TargetValue Akt1 (Cell-free Assay) 2.7 nM Akt3 (Cell-free Assay) 8.1 nM Akt2 (Cell-free Assay) 14 nM |
| Target | Value |
| Akt1 (Cell-free assay) | 2.7 nM |
| Akt3 (Cell-free assay) | 8.1 nM |
| Akt2 (Cell-free assay) | 14 nM |
Last Update：2024-04-09 19:05:03
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Spot supply
Product Name: ARQ-092 Visit Supplier Webpage Request for quotationCAS: 1313881-70-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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